Endocrine Abstracts

Although bilateral inferior petrosal sinus sampling (BIPSS) is the most accurate procedure for the differential diagnosis of ACTH-dependent Cushing’s syndrome, a false-negative rate of 4–15% has been reported. An even lower sensitivity has been shown in patients with equivocal responses to CRH and/or high-dose dexamethasone suppression test (HDST). In the present study we investigated whether the administration of CRH plus desmopressin (DDAVP) during BIPPS, which is ...